过去一年中添加的文章，按日期排序
Abstract PO4-28-08: Unraveling the Role of BRCA1-BARD1 E3 Ubiquitin Ligase in DNA Repair: A Promise for Enhanced Chemotherapy Outcomes
13 天前 - … The unveiling of BRCA1-BARD1 E3 ligase's intricate regulatory dynamics
combined with our novel mutants paves the way for an exciting new era in cancer therapeutics, …
combined with our novel mutants paves the way for an exciting new era in cancer therapeutics, …
A novel RB1 E3 ligase TRIM37 contributes to palbociclib resistance in breast cancer
C You, H Tsoi, PS Man, LKY Chow, W Dai, US Khoo - Cancer Research, 2024 - AACR
54 天前 - … ) is a RING finger E3 ubiquitin ligase and is a poor prognostic factor in breast cancer
… a region amplified in up to 40% of breast cancers. We observed that activation of androgen …
… a region amplified in up to 40% of breast cancers. We observed that activation of androgen …
MARCH2, a Novel Oncogene-regulated SNAIL E3 Ligase, Suppresses Triple-negative Breast Cancer Metastases
K Ito, I Harada, C Martinez, K Sato, EJ Lee, E Port… - Cancer Research …, 2024 - AACR
68 天前 - … E3 ligases (18, 19). In contrast, acetylation of SNAIL prevents its recognition by E3
ubiquitin ligases … EMT and metastasis of triple-negative breast cancer (TNBC) cells driven by …
ubiquitin ligases … EMT and metastasis of triple-negative breast cancer (TNBC) cells driven by …
NNMT/1‐MNA Promote Cell‐Cycle Progression of Breast Cancer by Targeting UBC12/Cullin‐1‐Mediated Degradation of P27 Proteins
Y Ma, X Huang, Y Wang, Y Lei, J Yu, S Yu… - Advanced …, 2024 - Wiley Online Library
146 天前 - … as a novel driver of cell-cycle progression in breast cancer. NNMT, highly expressed
in … Cullin-1-RING E3 ubiquitin ligase(CRL1)—an E3 ubiquitin ligase targeting p27 proteins. …
in … Cullin-1-RING E3 ubiquitin ligase(CRL1)—an E3 ubiquitin ligase targeting p27 proteins. …
RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer
E Prokakis, S Jansari, A Boshnakovska, M Wiese… - Cell Death & …, 2023 - nature.com
230 天前 - … Collectively, this study unveils a novel tumor-supportive … the Ring Finger Protein
40 (RNF40) E3 ligase responsible … stem cell properties of normal breast tissue and basal-like …
40 (RNF40) E3 ligase responsible … stem cell properties of normal breast tissue and basal-like …